Carboxylic acid salts
Sigma Aldrich Fine Chemicals Biosciences Methyl Red sodium salt ACS reagent, Dye content 95 % | 845-10-3 | MFCD00002426 | 25G
Methyl Red sodium salt ACS reagent, Dye content 95 % | Mol Wt: 291.28 | 845-10-3 | MFCD00002426 | 25G
Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 50mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
Apexbio Technology LLC Cefazolin (sodium salt) 27164-46-1 10mM (in 1mL DMSO)
Cefazolin sodium salt (CAS 27164-46-1) is a semisynthetic antibiotic that inhibits bacterial cell wall synthesis by binding to specific penicillin-binding proteins thereby blocking transpeptidation reactions essential for peptidoglycan formation In in vitro studies cefazolin sodium salt suppresses the proliferation of cultured osteoblast-like MG-63 cells exhibiting substantial cytotoxicity at concentrations of 10 000 g/ml precise IC50 values depend on cell type and experimental conditions Cefazolin sodium salt is commonly used in microbiology pharmacokinetic investigations and infection models particularly within studies of antimicrobial susceptibility and renal dysfunction
Apexbio Technology LLC Moxalactam (sodium salt) 64953-12-4 500mg
Moxalactam sodium salt (CAS 64953-12-4) is a small-molecule -lactam antibiotic belonging to the oxacephem subclass It is designed to inhibit bacterial cell wall biosynthesis by targeting penicillin-binding proteins (PBPs) Moxalactam sodium salt exerts its biological activity by interfering with PBPs thereby preventing cell wall synthesis In in vitro studies Moxalactam sodium salt demonstrates broad-spectrum inhibition of various Gram-positive Gram-negative and anaerobic bacteria including Klebsiella pneumoniae Escherichia coli Haemophilus influenzae and Neisseria gonorrhoeae Typical MIC values for susceptible organisms are generally in the low microgram-per-milliliter range Based on these pharmacological properties Moxalactam sodium salt holds research potential in antibacterial susceptibility assays studies on antibiotic resistance mechanisms and investigations of bacterial cell-wall synthesis pathways
Apexbio Technology LLC GSK1349572 sodiuM salt 1051375-19-9 50mg
GSK1349572 sodium salt (CAS 1051375-19-9) is a small-molecule inhibitor targeting HIV integrase It is designed to inhibit the integrase-mediated strand transfer process thereby blocking the integration of viral DNA into the host genome GSK1349572 sodium salt exerts its biological activity primarily through interaction with the enzyme s two-metal ion catalytic site inhibiting strand transfer In in vitro studies GSK1349572 sodium salt demonstrates potent antiviral inhibition with a protein-adjusted IC50 of approximately 38 nM in the presence of 100% human serum Based on these pharmacological properties GSK1349572 sodium salt holds research potential in antiviral studies evaluation of resistance profiles and drug development of integrase inhibitors for HIV therapy
Apexbio Technology LLC GSK1349572 sodiuM salt 1051375-19-9 100mg
GSK1349572 sodium salt (CAS 1051375-19-9) is a small-molecule inhibitor targeting HIV integrase It is designed to inhibit the integrase-mediated strand transfer process thereby blocking the integration of viral DNA into the host genome GSK1349572 sodium salt exerts its biological activity primarily through interaction with the enzyme s two-metal ion catalytic site inhibiting strand transfer In in vitro studies GSK1349572 sodium salt demonstrates potent antiviral inhibition with a protein-adjusted IC50 of approximately 38 nM in the presence of 100% human serum Based on these pharmacological properties GSK1349572 sodium salt holds research potential in antiviral studies evaluation of resistance profiles and drug development of integrase inhibitors for HIV therapy
Accela Chembio Inc Sodium Trimethylacetate Hydrate | 100g | 143174-36-1 | MFCD00150782 | 99% | Shelf Life: 1620 Days | Light Sensitive
Sodium Trimethylacetate Hydrate | 100g | 143174-36-1 | MFCD00150782 | 99% | Shelf Life: 1620 Days | Light Sensitive
Medchemexpress LLC 6-(3-hydroxypropyl)-2-(trimethyl-2-oxo-2,3-dihydro-benzimidazol-5-yl)-benzoisoquinoline-1,3-dione | 2080306-23-4 | MFCD30480933 | 99.4% | 429.47 g·mol⁻¹ | C25H23N3O4 | 50 MG
BAY-299 is a benzoisoquinolinedione chemical probe originally described by Bayer that potently inhibits the bromodomain-containing proteins BRPF2 (BRD1) and the second bromodomain of TAF1 and TAF1L. It is used in biochemical, structural, and cellular studies to probe bromodomain function and selectivity, with reported biochemical IC50s in the low-nanomolar range and validated activity in cell-based assays.
Sigma Aldrich Fine Chemicals Biosciences Sodium propionate-1-13C 99 atom % 13C | 62601-06-3 | MFCD00002758 | 250MG
Sodium propionate-1-13C 99 atom % 13C | Mol Wt: 97.05 | 62601-06-3 | MFCD00002758 | 250MG
Cayman Chemical Pravastatin sodium salt
A potent HMG-CoA reductase inhibitor (Ki = 2.3 nM); reduces total plasma cholesterol levels by 29% in dogs at 20 mg/kg per day for five weeks
Selleck Chemical LLC Nigericin sodium salt
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that works by acting as an H K and Pb2 ionophore Nigericin can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes
Apexbio Technology LLC Cefoxitin (sodium salt) 33564-30-6 1g
Cefoxitin sodium salt (CAS 33564-30-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby interfering with bacterial cell wall synthesis and peptidoglycan cross-linking Cefoxitin sodium salt exerts its biological activity primarily through inhibition of cell wall synthesis by binding to PBPs In in vitro enzymatic assays Cefoxitin sodium salt demonstrates inhibitory activity against various gram-positive and gram-negative bacteria with previously reported IC50 values in the low micromolar range due to its resistance to certain beta-lactamases including AmpC -lactamases Based on these pharmacological properties Cefoxitin sodium salt holds research potential in investigations of bacterial resistance mechanisms antimicrobial sensitivity profiling and beta-lactamase enzyme kinetics